Merck, Sanofi, and Eli Lilly joined the Series A financing of Therini Bio, a startup developing a drug that selectively targets fibrin as a way of reducing disease-driving inflammation in neurodegeneration and eye disorders such as diabetic macular edema. Therini is preparing to advance its lead program to clinical testing.

SR One’s new investment fund is its second one since spinning out of GSK in 2020. The firm says it now has more than $1.5 billion in assets under management.

GV led Chroma Medicine’s Series B financing round, which the biotech will apply toward epigenetic medicines that could offer advantages over other editing technologies. Other recent financings include rounds from Cargo Therapeutics and Transcend Therapeutics.

Miach Orthopaedics — a medical device company focused on restoring torn ACLs instead of reconstructing them — recently received $40 million in funding. The capital will be used to expand the U.S. commercial rollout of the company’s implantable device, which received FDA de novo clearance in 2020.

Taking inspiration from the success of drug cocktails that halt viral infections, startup IDRx aims to develop cancer drug combinations that stop tumor escape. The company, founded by serial entrepreneur Alexis Borisy, has set gastrointestinal stromal tumor (GIST) as its first disease target.

Exo recently partnered with Henry Ford Health to validate its software platform for point-of-care ultrasounds. The health system’s physicians will work with the company to increase the platform’s ease of use, as well as commercialize the mobile ultrasound device Exo is developing.

Tomorrow Health — a platform that makes it easier for patients, providers and payers to coordinate home-based care — closed a $60 million Series B funding round on Tuesday, bringing its total funding to date to $92.5 million. The startup will use the funds to expand its partnerships with payers, grow in new markets and further develop its technology.

Remote patient monitoring technology has been around for more than a decade, but health systems have had a difficult time scaling their programs. This is because the huge amount of data collected by RPM technology often creates more work for physicians, said Cadence CEO Chris Altchek.

Socially Determined, a healthcare analytics startup focused on social determinants of health insights, closed a $26 million funding round on Tuesday. It will used the funds to expand its customer base, which comprises health plans, health systems and life sciences organizations.

Medallion — a provider management platform that automates licensing, continuing education tracking, credentialing and compliance — has completed three funding rounds in one year. On Thursday, it closed a $35 million Series C round, which will be used to help the startup attract more hospital and health system customers.

Providence spun out Advata two weeks ago, and the startup, which has 30 customers and 150 employees, sells a suite of insights-focused data software products designed to improve population health and revenue cycle management.

PeerCapsule, a Phoenix-based company developing a collaboration platform for professional healthcare associations, recently received funding from AWS’ accelerator for early-stage startups led by founders from underrepresented groups. The startup will use the money to scale its platform and help build tools to enable faster clinical research.

Aidoc, a Tel Aviv-based startup providing software to help radiologists triage scans, closed a $110 million funding round on Thursday. The company will use the money to expand its AI platform and develop care coordination tools for various specialties instead of focusing solely on radiology.

Digital health startup K Health has teamed up with Mayo Clinic Platform to develop an algorithm to help clinicians provide personalized hypertension treatment. The model uses Mayo Clinic Platform’s collection of de-identified datasets from 10 million patients.

Online healthcare marketplace Sesame closed a $27 million Series B funding round on Tuesday, bringing its total funding to $75 million. David Goldhill, CEO of the New York City-based startup, said the company is “an Expedia for medical care” because patients can buy the care they want directly online, without the middleman of an insurance company.

Capital Rx recently closed a $106 million Series C funding round, bringing its overall funding to $175 million. The upstart pharmacy benefit manager will use the funds to enhance its digital pharmacy platform as well as grow its user base.

ImCheck Therapeutics aims to broaden the reach of cancer immunotherapy with antibody drugs that activate a rare but powerful type of immune cell called gamma delta T cells. The biotech has unveiled €96 million to advance its pipeline, including a lead candidate in development for both liquid and solid tumors.

Oben Health, a San Francisco-based company developing a digital treatment platform to fight heart disease without medication or surgery, recently received funding from AWS’ accelerator for early-stage startups led by founders from underrepresented groups. The startup will use the money to scale its platform and help conduct a pilot program to better understand its model’s clinical validity.

Check out news from Equiva, Healthmine, 9am.health, Forge Health and more.

Flume Health offers a platform for customized health plan administration for insurers who want to develop customized health plans to target certain populations. The company says it can bring tailored plans to the point of launch in just six months.

The company is developing a digital therapeutic using VR to manage chronic lower back pain. It recently submitted an application for de novo clearance to the FDA. 

Click Therapeutics is developing digital therapeutics for depression, insomnia and other conditions. It plans to use the funds to commercialize its therapeutics, through partnerships with pharmaceutical companies including Otsuka.

The Menlo Park-based company is building a service for quick at-home health services, such as lab draws and Covid-19 testing. The company is looking to build the “DoorDash for lab draws,” raising $33 million from backers.

Graphwear recently raised $20.5 million, which it plans to use to develop a CGM that uses nanotechnology to measure blood glucose levels. 

Consumers want the healthcare industry to meet them where they are, and this shift in patient mindset has expanded the definition of home healthcare and who benefits from it, according to a panel at MedCity INVEST Digital Health conference.

Tia, a concierge clinic combining primary care and OBGYN services, recently raised $100 million in funding. Amid a surge of financing into women’s health startups, CEO Carolyn Witte said investors’ perspectives are changing. 

Luminopia, a startup with a digital therapeutic for amblyopia, or lazy eye, recently published the results of a phase 3 study showing its TV-based treatment can improve vision in kids’ non-dominant eye. Patients don a headset where images are altered to make them use both eyes. 

Johnson & Johnson Impact Ventures and Village Capital launched their first accelerator focused on culturally competent care this summer. Two startups were each awarded $100,000: Omaiven Health and Lucia Health Guidelines.

Osso VR, which uses VR modules to prepare surgeons for hands-on training and demo medical devices, raised $27 million in funding. 

Five Blue Cross Blue Shield plans provided funding to establish Evio, which aims to improve clinical outcomes and cut drug costs. It will initially only offer services to the founding health plans, including data analytics to determine drug performance and enhancing outcomes-based contracting.